Mettl17 Gene Summary [Rat]

Predicted to enable 4 iron, 4 sulfur cluster binding activity; S-adenosyl-L-methionine binding activity; and mitochondrial ribosome binding activity. Predicted to be involved in mitochondrial small ribosomal subunit assembly. Predicted to be located in mitochondrial matrix and nucleoplasm. Orthologous to human METTL17 (methyltransferase like 17). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Mettl17
Official Name
methyltransferase like 17 [Source:RGD Symbol;Acc:1559895]
Ensembl ID
ENSRNOG00000025512
Bio databases IDs NCBI: 305845 Ensembl: ENSRNOG00000025512
Aliases methyltransferase like 17
Synonyms 2310032K15Rik, D14Ertd209e, methyltransferase like 17, METT11D1, RGD1559895
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Mettl17 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • binding protein
  • ribosome binding
  • protein binding
  • AdoMet_MTases
  • methyltransferase domain

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • preeclampsia
regulated by
role in cell
  • mitochondrial respiration in

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus
  • Mitochondria
  • mitochondrial matrix
  • nucleoplasm

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Mettl17 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • ribosomal small subunit biogenesis
  • translation

Cellular Component

Where in the cell the gene product is active
  • mitochondrial matrix
  • nucleoplasm

Molecular Function

What the gene product does at the molecular level
  • protein binding
  • metal ion binding
  • methyltransferase activity
  • 4 iron, 4 sulfur cluster binding

Gene-Specific Assays for Results You Can Trust

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