METTL17 Gene Summary [Human]
Predicted to enable S-adenosyl-L-methionine binding activity and mitochondrial ribosome binding activity. Predicted to be involved in ribosomal small subunit biogenesis. Located in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | METTL17 |
| Official Name | methyltransferase like 17 [Source:HGNC Symbol;Acc:HGNC:19280] |
| Ensembl ID | ENSG00000165792 |
| Bio databases IDs | |
| Aliases | methyltransferase like 17 |
| Synonyms | 2310032K15Rik, D14Ertd209e, methyltransferase like 17, METT11D1, RGD1559895 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human METTL17 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- binding protein
- ribosome binding
- protein binding
- AdoMet_MTases
- methyltransferase domain
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- Mitochondria
- mitochondrial matrix
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human METTL17 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- ribosomal small subunit biogenesis
- translation
Cellular Component
Where in the cell the gene product is active
- mitochondrial matrix
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- protein binding
- metal ion binding
- methyltransferase activity
- 4 iron, 4 sulfur cluster binding