Zar1 Gene Summary [Rat]
Predicted to enable RNA sequestering activity; mRNA 3'-UTR binding activity; and molecular condensate scaffold activity. Predicted to be involved in several processes, including membraneless organelle assembly; oocyte maturation; and post-transcriptional regulation of gene expression. Predicted to be located in cytoplasmic ribonucleoprotein granule. Predicted to be active in cytoplasm and intracellular membraneless organelle. Orthologous to human ZAR1 (zygote arrest 1). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Zar1 |
| Official Name | zygote arrest 1 [Source:RGD Symbol;Acc:727972] |
| Ensembl ID | ENSRNOG00000026150 |
| Bio databases IDs | |
| Aliases | zygote arrest 1 |
| Synonyms | Z3CXXC6, zygote arrest 1 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Zar1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- mRNA 3' UTR binding
- Zinc-binding domain
- protein binding activity, bridging
- protein binding
- translation regulator
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- organelle
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Zar1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- oocyte maturation
- mRNA stabilization
- negative regulation of translation
- translation
Cellular Component
Where in the cell the gene product is active
- cytoplasm
- intracellular non-membrane-bounded organelle
Molecular Function
What the gene product does at the molecular level
- protein binding
- metal ion binding
- mRNA 3'-UTR binding