ZAR1 Gene Summary [Human]
This maternal effect gene is oocyte-specific and encodes a protein that is thought to function in the initiation of embryogenesis. A similar protein in mouse is required for female fertility. [provided by RefSeq, Jul 2013]
Details
| Type | Protein Coding |
| Official Symbol | ZAR1 |
| Official Name | zygote arrest 1 [Source:HGNC Symbol;Acc:HGNC:20436] |
| Ensembl ID | ENSG00000182223 |
| Bio databases IDs | |
| Aliases | zygote arrest 1, zinc finger, 3CxxC-type 6 |
| Synonyms | Z3CXXC6, zygote arrest 1 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human ZAR1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- mRNA 3' UTR binding
- Zinc-binding domain
- protein binding activity, bridging
- protein binding
- translation regulator
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- organelle
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human ZAR1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- oocyte maturation
- mRNA stabilization
- negative regulation of translation
- translation
Cellular Component
Where in the cell the gene product is active
- cytoplasm
- intracellular non-membrane-bounded organelle
Molecular Function
What the gene product does at the molecular level
- protein binding
- metal ion binding
- mRNA 3'-UTR binding