Usp54 Gene Summary [Rat]

Predicted to enable K63-linked deubiquitinase activity and cysteine-type deubiquitinase activity. Predicted to be involved in protein deubiquitination and proteolysis. Orthologous to human USP54 (ubiquitin specific peptidase 54). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Usp54
Official Name
ubiquitin specific peptidase 54 [Source:RGD Symbol;Acc:1303206]
Ensembl ID
ENSRNOG00000027012
Bio databases IDs NCBI: 408223 Ensembl: ENSRNOG00000027012
Aliases ubiquitin specific peptidase 54
Synonyms 4930429G18RIK, bA137L10.3, bA137L10.4, C030002J06RIK, C10orf29, ubiquitin specific peptidase 54
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Usp54 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • peptidase
  • ubiquitin-specific protease
  • Ubiquitin carboxyl-terminal hydrolase
  • protein binding
  • Peptidase_C19
  • ubiquitin-like-specific protease

Pathways

Biological processes and signaling networks where the Usp54 gene in rat plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • venous thromboembolism
regulated by
  • dexamethasone
  • dihydrotestosterone
  • NR3C1
  • MYC
  • PCM1
  • Bacillus anthracis Sterne strain 7702

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Unknown

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Usp54 gene, providing context for its role in the cell.

Molecular Function

What the gene product does at the molecular level
  • ubiquitin-specific protease activity
  • protein binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.