Srsf7 Gene Summary [Rat]
Predicted to enable mRNA binding activity and protein domain specific binding activity. Predicted to be involved in mRNA cis splicing, via spliceosome and negative regulation of mRNA splicing, via spliceosome. Predicted to act upstream of or within cellular response to leukemia inhibitory factor. Predicted to be located in nucleoplasm. Predicted to be active in nuclear speck. Orthologous to human SRSF7 (serine and arginine rich splicing factor 7). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Srsf7 |
| Official Name | serine and arginine rich splicing factor 7 [Source:RGD Symbol;Acc:1307425] |
| Ensembl ID | ENSRNOG00000027360 |
| Bio databases IDs | |
| Aliases | serine and arginine rich splicing factor 7 |
| Synonyms | 9430065L19Rik, 9G8, AAG3, HSSG1, NX-96, serine and arginine-rich splicing factor 7, SFRS7 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Srsf7 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Zinc knuckle
- RNA recognition motif (RRM) superfamily
- zinc finger
- RNA recognition motif
- protein domain specific binding
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- spliceosomes
- nucleoplasm
- nucleoli
- interchromatin granule clusters
- stress granule
- paraspeckle-like structures
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Srsf7 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- RNA splicing
- negative regulation of nuclear mRNA splicing, via spliceosome
- mRNA processing
- mRNA transport
- nuclear mRNA splicing, via spliceosome
Cellular Component
Where in the cell the gene product is active
- nucleus
- extracellular vesicular exosome
- cytoplasm
- nuclear speck
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- zinc ion binding
- protein domain specific binding
- protein binding
- RNA binding
- mRNA binding