Sdhaf4 Gene Summary [Rat]

Predicted to enable enzyme activator activity. Involved in cellular respiration and mitochondrial respiratory chain complex II assembly. Predicted to be located in mitochondrial matrix. Predicted to be active in mitochondrion. [provided by Alliance of Genome Resources, Apr 2022]

Details

Type
Protein Coding
Official Symbol
Sdhaf4
Official Name
succinate dehydrogenase complex assembly factor 4 [Source:RGD Symbol;Acc:1588998]
Ensembl ID
ENSRNOG00000028087
Bio databases IDs NCBI: 685888 Ensembl: ENSRNOG00000028087
Aliases succinate dehydrogenase complex assembly factor 4
Synonyms 1110058L19Rik, 1700001E18Rik, C6orf57, LOC684207, Sdh8, succinate dehydrogenase complex assembly factor 4
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Sdhaf4 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Protein of unknown function (DUF1674)
  • enzyme
  • protein binding
  • enzyme activator activity

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • non-insulin-dependent diabetes mellitus
  • prostatic carcinoma
  • prostate cancer
  • epithelial cancer
role in cell
  • respiration

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • Mitochondria
  • mitochondrial matrix

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Sdhaf4 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • innate immune response
  • cellular respiration
  • mitochondrial respiratory chain complex II assembly

Cellular Component

Where in the cell the gene product is active
  • mitochondrial matrix
  • mitochondrion

Molecular Function

What the gene product does at the molecular level
  • protein binding
  • enzyme activator activity

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.