Dhrsx Gene Summary [Rat]
Predicted to enable dolichal reductase [NAD(P)+] activity and polyprenol dehydrogenase activity. Predicted to be involved in dolichol biosynthetic process and positive regulation of autophagy. Predicted to be active in extracellular region and lipid droplet. Orthologous to human DHRSX (dehydrogenase/reductase X-linked). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Dhrsx |
| Official Name | dehydrogenase/reductase X-linked [Source:RGD Symbol;Acc:1305017] |
| Ensembl ID | ENSRNOG00000028323 |
| Bio databases IDs | |
| Aliases | dehydrogenase/reductase X-linked |
| Synonyms | CAAA01118383.1, CDG1DD, CXorf11, D4Ertd296e, dehydrogenase/reductase X-linked, DHRS5X, DHRS5Y, DHRSXY, DHRSY, LOC100046538, Pscad, SDR46C1, SDR7C6 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Dhrsx often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Rossmann-fold NAD(P)(+)-binding proteins
- CH-CH group:NAD or NADP oxidoreductase
- enzyme
- protein binding
- short chain dehydrogenase
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
- lipid droplets
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Dhrsx gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- positive regulation of autophagy
Cellular Component
Where in the cell the gene product is active
- extracellular region
Molecular Function
What the gene product does at the molecular level
- protein binding
- oxidoreductase activity