DHRSX Gene Summary [Human]

Predicted to enable oxidoreductase activity. Involved in positive regulation of autophagy. Located in extracellular region. [provided by Alliance of Genome Resources, Apr 2022]

Details

Type
Protein Coding
Official Symbol
DHRSX
Official Name
dehydrogenase/reductase X-linked [Source:HGNC Symbol;Acc:HGNC:18399]
Ensembl ID
ENSG00000169084
Bio databases IDs NCBI: 207063 Ensembl: ENSG00000169084
Aliases dehydrogenase/reductase X-linked, short chain dehydrogenase/reductase family 7C, member 6, short chain dehydrogenase/reductase family 46C, member 1, dehydrogenase/reductase (SDR family) Y-linked
Synonyms CAAA01118383.1, CDG1DD, CXorf11, D4Ertd296e, dehydrogenase/reductase X-linked, DHRS5X, DHRS5Y, DHRSXY, DHRSY, LOC100046538, Pscad, SDR46C1, SDR7C6
Species
Human, Homo sapiens
OrthologiesRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human DHRSX often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Rossmann-fold NAD(P)(+)-binding proteins
  • CH-CH group:NAD or NADP oxidoreductase
  • enzyme
  • protein binding
  • short chain dehydrogenase

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • postmenopausal osteoporosis
  • Klinefelter syndrome
  • Turner syndrome
  • congenital disorders of glycosylation
role in cell
  • autophagy by

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Extracellular Space
  • lipid droplets

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human DHRSX gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • positive regulation of autophagy

Cellular Component

Where in the cell the gene product is active
  • extracellular region

Molecular Function

What the gene product does at the molecular level
  • protein binding
  • oxidoreductase activity

Gene-Specific Assays for Results You Can Trust

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