Tmem86b Gene Summary [Rat]

Enables alkenylglycerophosphocholine hydrolase activity; alkenylglycerophosphoethanolamine hydrolase activity; and identical protein binding activity. Involved in ether lipid metabolic process. Located in cytoplasm and membrane. [provided by Alliance of Genome Resources, Apr 2022]

Details

Type
Protein Coding
Official Symbol
Tmem86b
Official Name
transmembrane protein 86B [Source:RGD Symbol;Acc:1593455]
Ensembl ID
ENSRNOG00000038607
Bio databases IDs NCBI: 690610 Ensembl: ENSRNOG00000038607
Aliases transmembrane protein 86B
Synonyms C330014O21Rik, LOC684090, transmembrane protein 86B
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Tmem86b often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • alkenylglycerophosphocholine hydrolase
  • D-lysine 5,6-aminomutase
  • enzyme
  • protein binding
  • ether hydrolase
  • YhhN family
  • identical protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • systemic lupus erythematosus
regulated by
regulates
  • ether lipid
  • plasmalogens

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • cellular membrane
  • Plasma Membrane
  • cytosol
  • endoplasmic reticulum membrane

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Tmem86b gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • phosphatidylcholine acyl-chain remodeling
  • ether lipid metabolic process

Cellular Component

Where in the cell the gene product is active
  • endoplasmic reticulum membrane
  • cytoplasm
  • membrane

Molecular Function

What the gene product does at the molecular level
  • identical protein binding
  • protein binding
  • ether hydrolase activity
  • alkenylglycerophosphocholine hydrolase activity
  • D-lysine 5,6-aminomutase activity

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.