Nxf3 Gene Summary [Rat]

Predicted to enable mRNA binding activity. Predicted to be involved in poly(A)+ mRNA export from nucleus. Predicted to be located in cytoplasm and nucleoplasm. Predicted to be part of nuclear RNA export factor complex. Predicted to be active in nucleus. Orthologous to human NXF3 (nuclear RNA export factor 3). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Nxf3
Official Name
nuclear RNA export factor 3 [Source:RGD Symbol;Acc:1564923]
Ensembl ID
ENSRNOG00000028751
Bio databases IDs NCBI: 302591 Ensembl: ENSRNOG00000028751
Aliases nuclear RNA export factor 3
Synonyms Gm384, nuclear RNA export factor 3, RGD1564923, TAPL3, TAP-like protein 3
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Nxf3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • UBA domain-like superfamily
  • TAP C-terminal domain
  • mRNA binding
  • Tap, RNA-binding
  • protein binding
  • NTF2_like
  • RNA-binding domain
  • transporter

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • male infertility
regulated by
regulates

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus
  • Cytoplasm
  • nucleoplasm
  • nucleoli

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Nxf3 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • mRNA export from nucleus
  • poly(A)+ mRNA export from nucleus

Cellular Component

Where in the cell the gene product is active
  • nucleus
  • cytoplasm
  • nuclear RNA export factor complex
  • nucleoplasm

Molecular Function

What the gene product does at the molecular level
  • protein binding
  • RNA binding

Gene-Specific Assays for Results You Can Trust

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