Nxf3 Gene Summary [Mouse]
Enables mRNA binding activity. Acts upstream of or within poly(A)+ mRNA export from nucleus. Located in cytoplasm. Is expressed in testis. Orthologous to human NXF3 (nuclear RNA export factor 3). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Nxf3 |
| Official Name | nuclear RNA export factor 3 [Source:MGI Symbol;Acc:MGI:2685230] |
| Ensembl ID | ENSMUSG00000057000 |
| Bio databases IDs | |
| Aliases | nuclear RNA export factor 3 |
| Synonyms | Gm384, nuclear RNA export factor 3, RGD1564923, TAPL3, TAP-like protein 3 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Nxf3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- UBA domain-like superfamily
- TAP C-terminal domain
- mRNA binding
- Tap, RNA-binding
- protein binding
- NTF2_like
- RNA-binding domain
- transporter
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- Cytoplasm
- nucleoplasm
- nucleoli
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Nxf3 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- mRNA export from nucleus
- poly(A)+ mRNA export from nucleus
Cellular Component
Where in the cell the gene product is active
- nucleus
- cytoplasm
- nuclear RNA export factor complex
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- protein binding
- RNA binding