Zdhhc14 Gene Summary [Rat]

Predicted to enable protein-cysteine S-palmitoyltransferase activity. Predicted to be involved in peptidyl-L-cysteine S-palmitoylation and protein targeting to membrane. Predicted to be located in membrane. Predicted to be active in Golgi apparatus and endoplasmic reticulum. Orthologous to human ZDHHC14 (zinc finger DHHC-type palmitoyltransferase 14). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Zdhhc14
Official Name
zinc finger, DHHC-type containing 14 [Source:RGD Symbol;Acc:1565877]
Ensembl ID
ENSRNOG00000029049
Bio databases IDs NCBI: 499014 Ensembl: ENSRNOG00000029049
Aliases zinc finger, DHHC-type containing 14
Synonyms B530001K09Rik, Dhhc14, MGC29194, NEW1CP, zinc finger, DHHC domain containing 14, zinc finger DHHC-type palmitoyltransferase 14
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Zdhhc14 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • palmitoyltransferase
  • DHHC palmitoyltransferase
  • enzyme

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • peripheral neuropathy
  • lung adenocarcinoma
  • COVID-19
  • lung adenocarcinoma formation
regulated by
regulates
role in cell
  • palmitoylation in

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • cellular membrane
  • Endoplasmic Reticulum

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Zdhhc14 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • peptidyl-L-cysteine S-palmitoylation
  • protein palmitoylation
  • protein targeting to membrane

Cellular Component

Where in the cell the gene product is active
  • endoplasmic reticulum membrane
  • Golgi cisterna membrane
  • Golgi apparatus
  • endoplasmic reticulum

Molecular Function

What the gene product does at the molecular level
  • protein-cysteine S-palmitoleyltransferase activity
  • palmitoyltransferase activity

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.