Tafa3 Gene Summary [Rat]
Predicted to enable receptor ligand activity. Predicted to be involved in negative regulation of microglial cell activation and positive regulation of microglial cell activation. Predicted to be active in extracellular space. Orthologous to human TAFA3 (TAFA chemokine like family member 3). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Tafa3 |
| Official Name | TAFA chemokine like family member 3 [Source:RGD Symbol;Acc:1587462] |
| Ensembl ID | ENSRNOG00000030253 |
| Bio databases IDs | |
| Aliases | TAFA chemokine like family member 3 |
| Synonyms | 7530404M11Rik, FAM19A3, LOC684044, Sam3, TAFA chemokine like family member 3 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Tafa3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- TAFA family
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
- cell surface
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Tafa3 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- signal transduction
- neuroblast differentiation
Cellular Component
Where in the cell the gene product is active
- extracellular space
Molecular Function
What the gene product does at the molecular level
- receptor agonist activity