Csmd1 Gene Summary [Rat]
Predicted to enable serine-type endopeptidase activity. Predicted to act upstream of or within several processes, including learning or memory; mammary gland branching involved in pregnancy; and reproductive structure development. Predicted to be located in membrane. Predicted to be active in extracellular space. Orthologous to human CSMD1 (CUB and Sushi multiple domains 1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Csmd1 |
| Official Name | CUB and Sushi multiple domains 1 [Source:RGD Symbol;Acc:1305103] |
| Ensembl ID | ENSRNOG00000030719 |
| Bio databases IDs | |
| Aliases | CUB and Sushi multiple domains 1 |
| Synonyms | B930082H09, CUB and Sushi multiple domains 1, Mdcr1, mKIAA1890, PPP1R24 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Csmd1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- CCP
- CUB
- protein binding
- Sushi repeat (SCR repeat)
- SUSHI repeat
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- insulin resistance
- asthma
- chronic bronchitis
- chronic obstructive pulmonary disease
- lung cancer
- hepatitis B
- malaria
- non-insulin-dependent diabetes mellitus
- Alzheimer disease
- metabolic syndrome X
regulated by
- EBV strain 2089
- cephaloridine
- topotecan
- FUS
regulates
- D-glucose
role in cell
- stabilization
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- cellular membrane
- growth cone
- filopodia
- perikaryon
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Csmd1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- startle response
- male gonad development
- glucose homeostasis
- mammary gland branching involved in pregnancy
- oviduct epithelium development
- female gonad development
- memory
Cellular Component
Where in the cell the gene product is active
- membrane
Molecular Function
What the gene product does at the molecular level
- protein binding