Mab21l2 Gene Summary [Rat]
Predicted to be involved in eye development. Predicted to act upstream of or within camera-type eye development; embryonic body morphogenesis; and positive regulation of cell population proliferation. Predicted to be located in cytoplasm and nucleus. Human ortholog(s) of this gene implicated in coloboma and syndromic microphthalmia 14. Orthologous to human MAB21L2 (mab-21 like 2). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Mab21l2 |
| Official Name | mab-21 like 2 [Source:RGD Symbol;Acc:1595520] |
| Ensembl ID | ENSRNOG00000031398 |
| Bio databases IDs | |
| Aliases | mab-21 like 2 |
| Synonyms | LOC683881, mab-21-like 2, MCOPS14, MCSKS14 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Mab21l2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Mab-21 protein HhH/H2TH-like domain
- Mab-21 protein nucleotidyltransferase domain
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- Cytoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Mab21l2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- cell proliferation
- eye development
- embryonic body morphogenesis
- camera-type eye development
- positive regulation of cell proliferation
- nervous system development
Cellular Component
Where in the cell the gene product is active
- nucleus
- cytoplasm
Molecular Function
What the gene product does at the molecular level
- protein binding