Morc1 Gene Summary [Rat]
Predicted to enable zinc ion binding activity. Predicted to be involved in negative regulation of gene expression. Predicted to act upstream of or within several processes, including behavioral fear response; epigenetic regulation of gene expression; and negative regulation of DNA-templated transcription initiation. Predicted to be active in male germ cell nucleus. Orthologous to human MORC1 (MORC family CW-type zinc finger 1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Morc1 |
| Official Name | MORC family CW-type zinc finger 1 [Source:RGD Symbol;Acc:1565610] |
| Ensembl ID | ENSRNOG00000032101 |
| Bio databases IDs | |
| Aliases | MORC family CW-type zinc finger 1 |
| Synonyms | CT33, microrchidia 1, MORC, MORC family CW-type zinc finger 1, RGD1565610, ZCW6 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Morc1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- CW-type Zinc Finger
- Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
- Histidine kinase-like ATPase domain
- protein binding
- Morc6 ribosomal protein S5 domain 2-like
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Morc1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- transposition, RNA-mediated
- spermatogenesis
- cell differentiation
- gene silencing by RNA
- negative regulation of transcription initiation, DNA-dependent
- behavioral fear response
Cellular Component
Where in the cell the gene product is active
- nucleus
- male germ cell nucleus
Molecular Function
What the gene product does at the molecular level
- zinc ion binding