Als2cl Gene Summary [Rat]
Predicted to enable guanyl-nucleotide exchange factor activity and small GTPase binding activity. Predicted to be involved in endosomal transport. Predicted to act upstream of or within protein localization. Predicted to be active in cytoplasmic vesicle. Orthologous to human ALS2CL (ALS2 C-terminal like). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Als2cl |
| Official Name | ALS2 C-terminal like [Source:RGD Symbol;Acc:1305208] |
| Ensembl ID | ENSRNOG00000033921 |
| Bio databases IDs | |
| Aliases | ALS2 C-terminal like |
| Synonyms | 79H19D, 79H19E, ALS2 C-terminal like, BC022645, D930044G19Rik, FLJ36525, mRn.49018, RGD1305208, RN49018 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Als2cl often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Membrane Occupation and Recognition Nexus motif
- MORN repeat
- VPS9p domain
- Vacuolar sorting protein 9 (VPS9) domain
- enzyme binding
- protein binding
- Pleckstrin homology-like domain
- identical protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cytosol
- cytoplasmic vesicles
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Als2cl gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- regulation of GTPase activity
- endosomal transport
Cellular Component
Where in the cell the gene product is active
- cytoplasm
- cytoplasmic vesicle
- cytosol
Molecular Function
What the gene product does at the molecular level
- protein binding
- GTPase activator activity
- guanyl-nucleotide exchange factor activity
- small GTPase binding