Defb28 Gene Summary [Rat]
Defensins form a family of antimicrobial and cytotoxic peptides made by neutrophils. Defensins are short, processed peptide molecules that are classified by structure into three groups: alpha-defensins, beta-defensins and theta-defensins. All beta-defensin genes are densely clustered in four to five syntenic chromosomal regions. [provided by RefSeq, Oct 2014]
Details
| Type | Protein Coding |
| Official Symbol | Defb28 |
| Official Name | defensin beta 28 [Source:RGD Symbol;Acc:1565792] |
| Ensembl ID | ENSRNOG00000036900 |
| Bio databases IDs | |
| Aliases | defensin beta 28 |
| Synonyms | DEFB-15, Defb28, defensin beta 115, defensin beta 28, defensin β 115, defensin β 28, Gm1635 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Defb28 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Beta defensin
- protein binding
Pathways
Biological processes and signaling networks where the Defb28 gene in rat plays a role, providing insight into its function and relevance in health or disease.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Defb28 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- defense response to Gram-negative bacterium
- innate immune response
Cellular Component
Where in the cell the gene product is active
- extracellular region
Molecular Function
What the gene product does at the molecular level
- protein binding