Defb28 Gene Summary [Mouse]

Orthologous to human DEFB115 (defensin beta 115). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Defb28
Official Name
defensin beta 28 [Source:MGI Symbol;Acc:MGI:3650536]
Ensembl ID
ENSMUSG00000074679
Bio databases IDs NCBI: 545475 Ensembl: ENSMUSG00000074679
Aliases defensin beta 28
Synonyms DEFB-15, Defb28, defensin beta 115, defensin beta 28, defensin β 115, defensin β 28, Gm1635
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Defb28 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Beta defensin
  • protein binding

Pathways

Biological processes and signaling networks where the Defb28 gene in mouse plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Extracellular Space

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Defb28 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • defense response to Gram-negative bacterium
  • innate immune response

Cellular Component

Where in the cell the gene product is active
  • extracellular region

Molecular Function

What the gene product does at the molecular level
  • protein binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.