Treml1 Gene Summary [Rat]
Predicted to be involved in calcium-mediated signaling and platelet activation. Predicted to be located in several cellular components, including Golgi apparatus; nuclear speck; and platelet alpha granule. Orthologous to human TREML1 (triggering receptor expressed on myeloid cells like 1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Treml1 |
| Official Name | triggering receptor expressed on myeloid cells-like 1 [Source:RGD Symbol;Acc:1565175] |
| Ensembl ID | ENSRNOG00000040109 |
| Bio databases IDs | |
| Aliases | triggering receptor expressed on myeloid cells-like 1 |
| Synonyms | dJ238O23.3, GLTL1825, PRO3438, RGD1565175, TLT-1, triggering receptor expressed on myeloid cells-like 1 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Treml1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- immunoreceptor tyrosine-based inhibition motif
- immunoglobulin domain
- Immunoglobulin like
- protein binding
- Immunoglobulin V-set domain
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- cell surface
- Plasma Membrane
- Golgi Apparatus
- cytosol
- nuclear speckles
- alpha granules
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Treml1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- innate immune response
- platelet activation
Cellular Component
Where in the cell the gene product is active
- platelet alpha granule
- nuclear speck
- membrane
- cytosol
- Golgi apparatus
- plasma membrane
- cell surface
Molecular Function
What the gene product does at the molecular level
- protein binding
- transmembrane signaling receptor activity