Epm2aip1 Gene Summary [Rat]

Predicted to enable identical protein binding activity. Predicted to be involved in positive regulation of glycogen biosynthetic process. Predicted to act upstream of or within positive regulation of glycogen (starch) synthase activity and response to insulin. Predicted to be located in cytoplasmic side of endoplasmic reticulum membrane and nucleus. Orthologous to human EPM2AIP1 (EPM2A interacting protein 1). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Epm2aip1
Official Name
EPM2A interacting protein 1 [Source:RGD Symbol;Acc:1310977]
Ensembl ID
ENSRNOG00000043006
Bio databases IDs NCBI: 316021 Ensembl: ENSRNOG00000043006
Aliases EPM2A interacting protein 1
Synonyms A930003G21Rik, EPM2A interacting protein 1, mKIAA0766
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Epm2aip1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Domain of unknown function (DUF4371)
  • protein binding
  • identical protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • breast cancer
regulated by
  • EGF
  • CX3CR1
  • Salmonella enterica serotype abortus equi lipopolysaccharide
  • TREM1
regulates
  • glycogen

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • Nucleus
  • Endoplasmic Reticulum

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Epm2aip1 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • glycogen biosynthetic process
  • response to insulin stimulus
  • positive regulation of glycogen biosynthetic process

Cellular Component

Where in the cell the gene product is active
  • nucleus

Molecular Function

What the gene product does at the molecular level
  • identical protein binding
  • protein binding

Gene-Specific Assays for Results You Can Trust

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