Epm2aip1 Gene Summary [Mouse]
Predicted to enable identical protein binding activity. Acts upstream of or within positive regulation of glycogen (starch) synthase activity; positive regulation of glycogen biosynthetic process; and response to insulin. Located in cytoplasmic side of endoplasmic reticulum membrane and nucleus. Is expressed in cerebral cortex ventricular layer; cortical plate; and embryo. Orthologous to human EPM2AIP1 (EPM2A interacting protein 1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Epm2aip1 |
| Official Name | EPM2A (laforin) interacting protein 1 [Source:MGI Symbol;Acc:MGI:1925031] |
| Ensembl ID | ENSMUSG00000046785 |
| Bio databases IDs | |
| Aliases | EPM2A (laforin) interacting protein 1 |
| Synonyms | A930003G21Rik, EPM2A interacting protein 1, mKIAA0766 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Epm2aip1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Domain of unknown function (DUF4371)
- protein binding
- identical protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Nucleus
- Endoplasmic Reticulum
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Epm2aip1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- glycogen biosynthetic process
- response to insulin stimulus
- positive regulation of glycogen biosynthetic process
Cellular Component
Where in the cell the gene product is active
- nucleus
Molecular Function
What the gene product does at the molecular level
- identical protein binding
- protein binding