Cpne2 Gene Summary [Rat]
Predicted to enable calcium-dependent phospholipid binding activity. Predicted to be involved in cellular response to calcium ion. Predicted to be located in cytoplasm and nucleus. Predicted to be active in plasma membrane. Orthologous to human CPNE2 (copine 2). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Cpne2 |
| Official Name | copine 2 [Source:RGD Symbol;Acc:1586036] |
| Ensembl ID | ENSRNOG00000043286 |
| Bio databases IDs | |
| Aliases | copine 2 |
| Synonyms | 3322401K10RIK, copine 2, copine II, COPN2, CPN2, LOC689288 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Cpne2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Copine
- von Willebrand factor (vWF) type A domain
- vWFA
- protein binding
- Protein kinase C conserved region 2 (CalB)
- C2 domain
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Nucleus
- Plasma Membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Cpne2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- cellular response to calcium ion
Cellular Component
Where in the cell the gene product is active
- nucleus
- extracellular vesicular exosome
- cytoplasm
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- protein binding
- metal ion binding
- calcium-dependent phospholipid binding