Mrgbp Gene Summary [Rat]

Predicted to be involved in histone acetylation and regulation of transcription by RNA polymerase II. Located in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

Details

Type
Protein Coding
Official Symbol
Mrgbp
Official Name
MRG domain binding protein [Source:RGD Symbol;Acc:1308612]
Ensembl ID
ENSRNOG00000045955
Bio databases IDs NCBI: 311713 Ensembl: ENSRNOG00000045955
Aliases MRG domain binding protein
Synonyms 1600027N09Rik, C20orf20, Eaf7, MRG15BP, MRG domain binding protein, MRG/MORF4L binding protein, NEWGENE 1308612, RGD1308612, URCC4
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Mrgbp often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Chromatin modification-related protein EAF7
  • protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
binds
regulates
  • PRKN
role in cell
  • cell cycle progression

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus
  • nucleosomes
  • nucleoplasm

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Mrgbp gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • regulation of double-strand break repair
  • positive regulation of transcription, DNA-dependent
  • regulation of apoptotic process
  • regulation of cell cycle
  • chromatin organization
  • regulation of transcription from RNA polymerase II promoter

Cellular Component

Where in the cell the gene product is active
  • NuA4 histone acetyltransferase complex
  • nucleosome
  • nucleoplasm

Molecular Function

What the gene product does at the molecular level
  • protein binding

Gene-Specific Assays for Results You Can Trust

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