MRGBP Gene Summary [Human]
Predicted to be involved in histone acetylation and regulation of transcription by RNA polymerase II. Located in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | MRGBP |
| Official Name | MRG domain binding protein [Source:HGNC Symbol;Acc:HGNC:15866] |
| Ensembl ID | ENSG00000101189 |
| Bio databases IDs | |
| Aliases | MRG domain binding protein |
| Synonyms | 1600027N09Rik, C20orf20, Eaf7, MRG15BP, MRG domain binding protein, MRG/MORF4L binding protein, NEWGENE 1308612, RGD1308612, URCC4 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human MRGBP often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Chromatin modification-related protein EAF7
- protein binding
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- nucleosomes
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human MRGBP gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- regulation of double-strand break repair
- positive regulation of transcription, DNA-dependent
- regulation of apoptotic process
- regulation of cell cycle
- chromatin organization
- regulation of transcription from RNA polymerase II promoter
Cellular Component
Where in the cell the gene product is active
- NuA4 histone acetyltransferase complex
- nucleosome
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- protein binding