Cdhr3 Gene Summary [Rat]

Predicted to enable calcium ion binding activity. Predicted to be involved in cell adhesion. Predicted to be active in plasma membrane. Orthologous to human CDHR3 (cadherin related family member 3). [provided by Alliance of Genome Resources, Apr 2025]

Details

Type
Protein Coding
Official Symbol
Cdhr3
Official Name
cadherin-related family member 3 [Source:RGD Symbol;Acc:1591286]
Ensembl ID
ENSRNOG00000047455
Bio databases IDs NCBI: 686932 Ensembl: ENSRNOG00000047455
Aliases cadherin-related family member 3
Synonyms 1110049B09Rik, cadherin-related family member 3, CDH28, LOC100506768
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Cdhr3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Cadherin-like
  • Cadherin repeat-like domain
  • protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • atrial fibrillation
  • asthma
  • nonsyndromic otitis media
regulated by
role in cell
  • binding
  • replication in

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Plasma Membrane

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Cdhr3 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • viral entry into host cell
  • calcium-dependent cell-cell adhesion
  • adherens junction organization
  • cell-cell junction assembly
  • multicellular organismal development
  • cell morphogenesis
  • cell-cell adhesion mediated by cadherin
  • homophilic cell adhesion
  • cell migration

Cellular Component

Where in the cell the gene product is active
  • adherens junction
  • synaptic cleft
  • catenin complex
  • plasma membrane
  • axon terminus

Molecular Function

What the gene product does at the molecular level
  • protein binding
  • cadherin binding
  • calcium ion binding
  • viral receptor activity
  • beta-catenin binding

Gene-Specific Assays for Results You Can Trust

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