CDHR3 Gene Summary [Human]
Predicted to enable cadherin binding activity and calcium ion binding activity. Predicted to be involved in calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules; cell morphogenesis; and cell-cell junction organization. Located in plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Processed Transcript |
| Official Symbol | CDHR3 |
| Official Name | cadherin related family member 3 [Source:HGNC Symbol;Acc:HGNC:26308] |
| Ensembl ID | ENSG00000128536 |
| Bio databases IDs | |
| Aliases | cadherin related family member 3 |
| Synonyms | 1110049B09Rik, cadherin-related family member 3, CDH28, LOC100506768 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human CDHR3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Cadherin-like
- Cadherin repeat-like domain
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human CDHR3 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- viral entry into host cell
- calcium-dependent cell-cell adhesion
- adherens junction organization
- cell-cell junction assembly
- multicellular organismal development
- cell morphogenesis
- cell-cell adhesion mediated by cadherin
- homophilic cell adhesion
- cell migration
Cellular Component
Where in the cell the gene product is active
- adherens junction
- synaptic cleft
- catenin complex
- plasma membrane
- axon terminus
Molecular Function
What the gene product does at the molecular level
- protein binding
- cadherin binding
- calcium ion binding
- viral receptor activity
- beta-catenin binding