Ak7 Gene Summary [Rat]

Predicted to enable (d)CMP kinase activity; adenylate kinase activity; and nucleoside diphosphate kinase activity. Predicted to be involved in nucleoside monophosphate phosphorylation. Predicted to act upstream of or within several processes, including axoneme assembly; epithelial cilium movement involved in extracellular fluid movement; and inflammatory response to antigenic stimulus. Predicted to be located in cytosol. Predicted to be active in cytoplasm. Human ortholog(s) of this gene implicated in spermatogenic failure 27. Orthologous to human AK7 (adenylate kinase 7). [provided by Alliance of Genome Resources, Apr 2025]

Details

Type
Protein Coding
Official Symbol
Ak7
Official Name
adenylate kinase 7 [Source:RGD Symbol;Acc:1309600]
Ensembl ID
ENSRNOG00000055714
Bio databases IDs NCBI: 314416 Ensembl: ENSRNOG00000055714
Aliases adenylate kinase 7
Synonyms 4930502N02RIK, adenylate kinase 7, CFAP75, FAP75, SPGF27
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Ak7 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • kinase
  • nucleoside diphosphate kinase
  • adenylate kinase
  • cytidylate kinase
  • DD_R_PKA_DPY30-like
  • Dpy-30 motif
  • AAA domain

Pathways

Biological processes and signaling networks where the Ak7 gene in rat plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • spermatogenic failure 27
  • primary ciliary dyskinesia
regulated by
regulates
  • MCL1
role in cell
  • assembly
  • movement
  • alternative splicing in

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • cytosol

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Ak7 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • cell projection organization
  • nucleoside monophosphate phosphorylation

Cellular Component

Where in the cell the gene product is active
  • motile cilium
  • cytoplasm
  • cytosol

Molecular Function

What the gene product does at the molecular level
  • adenylate kinase activity
  • ATP binding
  • cytidylate kinase activity
  • nucleoside diphosphate kinase activity

Gene-Specific Assays for Results You Can Trust

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