Cylc1

Predicted to enable protein homodimerization activity. Predicted to be involved in cytoskeleton organization. Predicted to act upstream of or within several processes, including acrosome assembly; maintenance of cell number; and single fertilization. Predicted to be located in cytoskeletal calyx and sperm head. Predicted to be active in acrosomal matrix; acrosomal membrane; and perinuclear theca. Human ortholog(s) of this gene implicated in X-linked spermatogenic failure 8. Orthologous to human CYLC1 (cylicin 1). [provided by Alliance of Genome Resources, Apr 2025]

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Cylc1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.

Describes the biological processes, cellular components, and molecular functions associated with the rat Cylc1 gene, providing context for its role in the cell.