Slc10a3 Gene Summary [Rat]

Predicted to enable bile acid:sodium symporter activity. Predicted to be involved in bile acid and bile salt transport. Predicted to act upstream of or within response to retinoic acid. Predicted to be located in membrane. Orthologous to human SLC10A3 (solute carrier family 10 member 3). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Slc10a3
Official Name
solute carrier family 10, member 3 [Source:RGD Symbol;Acc:1563513]
Ensembl ID
ENSRNOG00000060580
Bio databases IDs NCBI: 501665 Ensembl: ENSRNOG00000060580
Aliases solute carrier family 10, member 3
Synonyms DXHXS253E, DXS253E, DXS253Eh, DXSmhG28, P3, solute carrier family 10 member 3, solute carrier family 10, member 3, solute carrier family 10 (sodium/bile acid cotransporter family), member 3
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Slc10a3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • bile acid transporter
  • Sodium Bile acid symporter family
  • Predicted Na+-dependent transporter YfeH [General function prediction only]
  • transporter

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
regulated by

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Plasma Membrane
  • cellular membrane

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Slc10a3 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • response to retinoic acid
  • transmembrane transport
  • bile acid and bile salt transport

Cellular Component

Where in the cell the gene product is active
  • membrane

Molecular Function

What the gene product does at the molecular level
  • bile acid:sodium symporter activity

Gene-Specific Assays for Results You Can Trust

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