Taf9b Gene Summary [Rat]

Predicted to enable protein heterodimerization activity. Predicted to contribute to RNA polymerase II general transcription initiation factor activity. Involved in programmed cell death and response to thiabendazole. Predicted to be located in nucleus. Predicted to be part of transcription factor TFIID complex and transcription factor TFTC complex. Orthologous to human TAF9B (TATA-box binding protein associated factor 9b). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Taf9b
Official Name
TATA-box binding protein associated factor 9b [Source:RGD Symbol;Acc:621116]
Ensembl ID
ENSRNOG00000061102
Bio databases IDs NCBI: 171152 Ensembl: ENSRNOG00000061102
Aliases TATA-box binding protein associated factor 9b
Synonyms DN-7, TAF9L, TAFII31, TAFII31L, TATA-box binding protein associated factor 9B, TFIID-31
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Taf9b often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • histone fold domain (HFD) superfamily
  • Transcription initiation factor IID, 31kD subunit
  • CENP-S protein
  • transcription regulator
  • protein binding
  • Bromodomain associated

Pathways

Biological processes and signaling networks where the Taf9b gene in rat plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • androgenic alopecia
  • Rett syndrome
regulated by
regulates
  • RNA polymerase II
  • DNA promoter
  • DNA endogenous promoter
role in cell
  • apoptosis
  • growth

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus
  • nucleoplasm

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Taf9b gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • negative regulation of transcription from RNA polymerase II promoter
  • positive regulation of cell growth
  • negative regulation of apoptotic process
  • transcription from RNA polymerase II promoter
  • transcription initiation, DNA-dependent
  • protein stabilization

Cellular Component

Where in the cell the gene product is active
  • transcription factor TFIID complex
  • transcription factor TFTC complex
  • nucleoplasm

Molecular Function

What the gene product does at the molecular level
  • protein binding
  • transcription corepressor activity
  • protein heterodimerization activity
  • general RNA polymerase II transcription factor activity

Gene-Specific Assays for Results You Can Trust

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