Taf9b Gene Summary [Mouse]
Predicted to enable protein heterodimerization activity. Predicted to contribute to RNA polymerase II general transcription initiation factor activity. Predicted to be involved in several processes, including negative regulation of transcription by RNA polymerase II; positive regulation of cell growth; and protein stabilization. Predicted to be located in nucleus. Predicted to be part of transcription factor TFIID complex and transcription factor TFTC complex. Is expressed in tail. Orthologous to human TAF9B (TATA-box binding protein associated factor 9b). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Taf9b |
| Official Name | TATA-box binding protein associated factor 9B [Source:MGI Symbol;Acc:MGI:3039562] |
| Ensembl ID | ENSMUSG00000047242 |
| Bio databases IDs | |
| Aliases | TATA-box binding protein associated factor 9B |
| Synonyms | DN-7, TAF9L, TAFII31, TAFII31L, TATA-box binding protein associated factor 9B, TFIID-31 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Taf9b often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- histone fold domain (HFD) superfamily
- Transcription initiation factor IID, 31kD subunit
- CENP-S protein
- transcription regulator
- protein binding
- Bromodomain associated
Pathways
Biological processes and signaling networks where the Taf9b gene in mouse plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Taf9b gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- negative regulation of transcription from RNA polymerase II promoter
- positive regulation of cell growth
- negative regulation of apoptotic process
- transcription from RNA polymerase II promoter
- transcription initiation, DNA-dependent
- protein stabilization
Cellular Component
Where in the cell the gene product is active
- transcription factor TFIID complex
- transcription factor TFTC complex
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- protein binding
- transcription corepressor activity
- protein heterodimerization activity
- general RNA polymerase II transcription factor activity