Target List
Covers specific hotspots of the targeted genes based on the Human GRCh38 genome build
Hotspot Coverage
AKT1APCBRAFCTNNB1DPYDEGFR (ERBB1)FBXW7GNASMAP2K1NRASPIK3CA (p110-alpha)RETSMAD4 (MADH4)UGT1A1
Whole Coding Coverage
ERBB2 (HER-2, NEU)KRASTP53 (p53)
Adenocarcinomas
APCBRAFCTNNB1EGFR (ERBB1)ERBB2 (HER-2, NEU)FBXW7GNASKRASMAP2K1NRASRETSMAD4 (MADH4)TP53 (p53)
Metastatic Colorectal Cancers
AKT1BRAFCTNNB1EGFR (ERBB1)ERBB2 (HER-2, NEU)KRASMAP2K1NRASPIK3CA (p110-alpha)RET
Other Colorectal Cancer Genes
BRAFCTNNB1DPYDEGFR (ERBB1)ERBB2 (HER-2, NEU)KRASMAP2K1NRASPIK3CA (p110-alpha)RETUGT1A1