GeneGlobe ID: SBHS-027Z | Cat. No.: 249950 | QuantiNova LNA PCR Focus Panels

QuantiNova LNA PCR Focus Panel Human p53 Signaling Pathway

QuantiNova LNA PCR Focus Panel
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Product Specification

Target List
p53 Activation
ATM, ATR, BBC3 (PUMA), BRCA1, CDKN1A (p21CIP1, WAF1), CDKN2A (P16INK4A), CHEK1, CHEK2 (RAD53), FOXO3, GML, MDM2, MSH2, SIRT1, TP63, TP73
p53 Regulators & Interactors
CDKN2A (P16INK4A), DNMT1, HDAC1, KAT2B, MDM2, MDM4, SIRT1, TADA3, TP53AIP1, TP53BP2, TP63, TP73
p53 Targets
Apoptosis​
APAF1, BAX, BBC3 (PUMA), BTG2, CASP9, EGFR (ERBB1), EI24, ESR1 (ERα), FAS, PRKCA, TNF, TNFRSF10B (DR5), TP53 (p53), TP53AIP1, TP73
Cell Cycle​
CCNG1, CDC25A, CDC25C, CDKN1A (p21CIP1, WAF1), E2F1, E2F3, GML, MDM2, MYC, PPM1D, RB1, RPRM, SESN2, SIAH1
DNA Damage & Repair​
BRCA1, BTG2, EGFR (ERBB1), GADD45A, PCNA, PTTG1
Angiogenesis​
ADGRB1 (BAI1), IL6, PTEN
Responses Downstream of p53 Signaling
Apoptosis​
APAF1, BCL2, BCL2A1 (BFL1), BID, BIRC5, CASP2, CASP9, CRADD, FADD, FASLG (TNFSF6), IGF1R, MCL1, NF1, NFKB1, PIDD1 (PIDD), RELA, TNFRSF10D, TRAF2, WT1
Cell Cycle​
CCNB1, CCNE1, CCNG1, CCNH, CDK1, CDK4, PRC1, TSC1
DNA Damage & Repair​
BRCA2, MLH1, XRCC5
Transcription Factors & Regulators​
BRCA2, EGR1, JUN, MYOD1, NFKB1, RELA, STAT1
Other Responses Downstream of p53 Signaling​
HK2, KRAS
Gene Resource List
Array Layout for PCR Plates
File Size: 153.59 KBLanguage: English
Array Layout for Rotor-Gene Q
File Size: 153.72 KBLanguage: English

Resources

Quick-Start Protocols (1)
Safety Data Sheets (1)
Kit Handbooks (1)
Certificates of Analysis (1)
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