Target List
Neurotransmitter Receptors
Dopamine Receptors
DRD1, DRD2, DRD3, DRD4, DRD5
Serotonin (5-Hydroxytryptamine) Receptors
HTR1A, HTR1B, HTR1D, HTR1E, HTR1F, HTR2A, HTR2B, HTR2C, HTR3A, HTR3B, HTR4, HTR5A, HTR6, HTR7
Neurotransmitter Synthesis & Degradation
Dopamine Metabolism
COMT, DBH, DDC, MAOA, TH
Serotonin Metabolism
MAOA, MAOB, TDO2, TPH1, TPH2
Dopamine & Serotonin Transporters
SLC6A3 (DAT), SLC6A4 (SERT)
Signal Transduction
cAMP & Protein Kinase A Signaling
ADCY1, ADCY2, ADCY3, ADCY5, CASP3, CDK5, CREB1, DUSP1 (PTPN16), FOS, MAPK1 (ERK2), PPP1R1B (DARPP32), PRKACA
AKT & PI3 Kinase Signaling
AKT1, AKT2, AKT3, GSK3A, GSK3B, PIK3CA (p110-alpha), PIK3CG
Phospholipase A2 Pathway
ALOX12, CYP2D6, PDE10A, PDE4A, PDE4B, PDE4C (QuantiNova Symbol: AC008397.2), PDE4D, PLA2G5
Phospholipase C Signaling
ITPR1, PLCB1, PLCB2, PLCB3
G-Protein Coupled Receptor Regulation
ADRB1, ADRB2, APP, ARRB1, ARRB2, GRK2, GRK3, GRK4, GRK5, GRK6, SNCA, SNCAIP
Dopamine & Serotonin Gene Targets
BDNF, EPHB1, GDNF, GFAP, NR4A1 (NUR77), NR4A3 (NOR1), PDYN, PTGS2 (COX2), SLC18A1 (VMAT1), SLC18A2 (VMAT2), SYN2