GeneGlobe ID: PAHS-040Z | Cat. No.: 330231 | RT2 Profiler PCR Arrays

RT² Profiler™ PCR Array Human EGF / PDGF Signaling Pathway

RT2 Profiler PCR Array
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Product Specification

Target List
EGFR Signaling
BCAR1, CBL, EGF, EGFR (ERBB1), EPS8, GAB1, GRB2, HBEGF, NCK2, NUP62, RPS6KA5, SHC1
Platelet-Derived Growth Factor Receptor Signaling
BCAR1, PDGFA, PDGFB, PDGFRA, PLAT (TPA)
Intracellular Signaling
AKT Signaling​
AKT1, AKT2, AKT3, BAD, CASP9, CHUK (IKKα), FASLG (TNFSF6), FOXO3, NFKB1, PTEN
ERK1 / ERK2 Signaling​
EGFR (ERBB1), ELK1, GRB2, MAP2K1, MAPK1 (ERK2), MAPK3 (ERK1), MKNK1, PDGFRA, RAF1, RPS6KA5, SHC1, SRC, STAT3
IκB Kinase / NFκB Cascade​
CHUK (IKKα), FASLG (TNFSF6), GSK3A, GSK3B, NUP62, RHOA, STAT1
JAK / STAT Signaling​
EPS8, GAB1, GRB2, JAK1, NUP62, PPP2CA, SRC, STAT1, STAT3, STAT5A
JNK / p38 Signaling​
MAP2K4 (MKK4, JNKK1), MAP3K2 (MEKK2), MAPK10 (JNK3), MAPK8 (JNK1), MAPK9 (JNK2)
MAP Kinase Signaling​
DUSP1 (PTPN16), DUSP6, EGF, EGFR (ERBB1), MAP2K1, MAP2K7 (JNKK2), MAPK1 (ERK2), MAPK10 (JNK3), MAPK3 (ERK1), MAPK8 (JNK1), MAPK9 (JNK2), PPP2CA, PRKCA, SHC1
PI3 Kinase Signaling​
PIK3CA (p110-alpha), PIK3R1 (p85-ALPHA), PIK3R2 (p85-BETA), PTEN
G-Protein Signaling​
GRB2, HRAS, NRAS, NUP62, RAP1A, RASA1, RHOA
Other Intracellular Signaling Molecules​
ARAF, BRAF, CBL, CSNK2A1, CSNK2B, IKBKB (IKKβ), NCK2, PDPK1, PLCG1, RPS6KB1
Cell Survival & Growth
Apoptosis​
AKT1, BAD, BCAR1, BCL2, BRAF, CASP3, CASP9, FASLG (TNFSF6), FOXO3, IL2, LTA (TNFB), MAPK1 (ERK2), NFKB1, NUP62, PIK3R2 (p85-BETA), PPP2CA, PRKCA, PTEN, RAF1, RASA1, STAT1, TP53 (p53)
Cell Cycle​
BCL2, CCND1, DUSP1 (PTPN16), DUSP6, EGFR (ERBB1), HRAS, KRAS, MAPK1 (ERK2), MAPK3 (ERK1), NRAS, PDGFA, PDGFB, PPP2CA, PRKCA, PTEN, RAP1A, SHC1, STAT1, TP53 (p53)
Cell Differentiation​
FOXO3, IL2, PPP2CA, TP53 (p53)
Cell Growth​
BCAR1, CCND1, EGF, HBEGF, IL2, PDGFA, PDGFB, PDGFRA, PPP2CA, RASA1, SHC1, TP53 (p53)
Cell Motility​
ACTR2, BCAR1, EGFR (ERBB1), FN1, HBEGF, MAP2K1, MAPK8 (JNK1), PTEN, STAT3
Cell Proliferation​
BCAR1, BCL2, EGF, EGFR (ERBB1), EPS8, GAB1, HBEGF, IL2, NCK2, NUP62, PDGFA, PDGFB, PDGFRA, PTEN, RAF1, SHC1, TP53 (p53)
Metabolism
DNA Metabolism​
ATF1, ATF2 (CREB2), CREB1, EGF, EGFR (ERBB1), FOS, NUP62, PPP2CA, TP53 (p53)
Lipid Metabolism​
ARAF, BRAF, PIK3R1 (p85-ALPHA), PLCG1, PPP2CA, PRKCA, PTEN, RAF1, SHC1
Protein Metabolism​
ACTR2, AKT1, AKT2, AKT3, ARAF, ATF1, ATF2 (CREB2), BRAF, CBL, CHUK (IKKα), CREB1, CSNK2A1, DUSP1 (PTPN16), DUSP6, EGFR (ERBB1), FOS, GSK3A, GSK3B, IKBKB (IKKβ), JAK1, MAP2K1, MAP2K4 (MKK4, JNKK1), MAP2K7 (JNKK2), MAP3K2 (MEKK2), MAPK1 (ERK2), MAPK10 (JNK3), MAPK3 (ERK1), MAPK8 (JNK1), MAPK9 (JNK2), MKNK1, PDGFRA, PDPK1, PPP2CA, PRKCA, PTEN, RAF1, RPS6KA5, RPS6KB1, SRC
Other Metabolism Genes​
COL1A1, EIF4E, FN1, MMP7, RASA1
Development
BRAF, COL1A1, HBEGF, PTEN, RASA1, STAT3
Stimulus Response
Response to Wounding​
BCAR1, BCL2, FN1, HBEGF, IL2, NCK2, NFKB1, PDGFB, STAT3
Response to Other Stimuli​
AKT1, CHUK (IKKα), COL1A1, DUSP1 (PTPN16), EGFR (ERBB1), FASLG (TNFSF6), FOS, KRAS, LTA (TNFB), MAP2K1, MAP2K7 (JNKK2), MAPK1 (ERK2), MAPK8 (JNK1), MAPK9 (JNK2), NFATC3, PPP2CA, RPS6KA5, STAT1, STAT5A, TP53 (p53)
Transcription Factors & Regulators
AKT1, ATF1, ATF2 (CREB2), CBL, CREB1, EGR1, EIF4E, ELK1, FOS, FOXO3, IKBKB (IKKβ), JUN, MKNK1, NFATC3, NFKB1, NUP62, PPP2CA, RPS6KA5, STAT1, STAT3, STAT5A, TP53 (p53)
Actin & Calcium Ion Homeostasis
ACTR2, BCAR1, CBL, EGF, EGFR (ERBB1), MMP7, NCK2, PDPK1, PLCG1, PRKCA, RASA1, RHOA, STAT1, STAT3, STAT5A
Gene Resource List
Array Layout for PCR Plates
File Size: 137.85 KBLanguage: English
Array Layout for Rotor-Gene Q
File Size: 131.62 KBLanguage: English

Resources

Brochures & Guides (3)
Simultaneously profile mRNA, miRNA and lncRNA using a simple, complete workflow
Download Files (3)
For analyzing gene expression data from RT2 Profiler PCR Arrays 
Data analysis file for RT² Profiler PCR Array Housekeeping Genes
Catalog number- 330231
Pathway number- PAXX-000
RNA QC Data Analysis
XLS (484KB)

Data analysis file for RT² ProfilerRT² Profiler™ PCR Array RT2 RNA QC
Catalog number- 330231
Pathway number- PAXX-999

Scientific Posters (1)
Poster for download
Kit Handbooks (1)
For pathway-focused gene expression profiling using real-time RT-PCR
Instrument Technical Documents (2)
For gene expression and genomic analysis
For pathway-focused gene expression analysis
Certificates of Analysis (1)
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