Rab40b Gene Summary [Rat]
Predicted to enable GTPase activity. Predicted to be involved in cellular detoxification and exocytosis. Predicted to be located in nuclear envelope and perinuclear region of cytoplasm. Predicted to be active in endosome; plasma membrane; and synaptic vesicle. Orthologous to several human genes including RAB40B (RAB40B, member RAS oncogene family). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Rab40b |
| Official Name | Rab40b, member RAS oncogene family [Source:RGD Symbol;Acc:1305663] |
| Ensembl ID | ENSRNOG00000036661 |
| Bio databases IDs | |
| Aliases | Rab40b, member RAS oncogene family |
| Synonyms | RAB40B, member RAS oncogene family, RAR, Rar1, SEC4L |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Rab40b often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- SOCS box
- small GTP-binding protein domain
- Ras family
- Rab subfamily of small GTPases
- SOCS
- enzyme
- protein binding
- Ras of Complex, Roc, domain of DAPkinase
- Rho (Ras homology) subfamily of Ras-like small GTPases
- P-loop containing Nucleoside Triphosphate Hydrolases
- Ras subfamily of RAS small GTPases
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- Cytoplasm
- perinuclear region
- Golgi Apparatus
- Mitochondria
- lipid droplets
- nuclear envelope
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Rab40b gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- protein secretion
- exocytosis
- intracellular signal transduction
- protein ubiquitination
Cellular Component
Where in the cell the gene product is active
- nuclear envelope
- endosome
- perinuclear region of cytoplasm
- synaptic vesicle
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- GTP binding
- protein binding
- GTPase activity