Gzmf Gene Summary [Rat]
Predicted to enable serine-type endopeptidase activity. Predicted to be involved in protein maturation. Predicted to be active in extracellular space. Orthologous to human GZMH (granzyme H). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Gzmf |
| Official Name | granzyme F [Source:RGD Symbol;Acc:628603] |
| Ensembl ID | ENSRNOG00000028810 |
| Bio databases IDs | |
| Aliases | granzyme F |
| Synonyms | CCP3, CCP4, CCP5, Ctla-5, Ctla-6, Ctla-7, granzyme D, granzyme E, granzyme F, granzyme G, Grz d, Grz e, Grz f, Grz g, Gzmd, Gzme, Gzmg, LOC100910060, MCSP-2, MCSP-3, Rnkp7 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Gzmf often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Trypsin-like serine protease
- trypsin
- Tryp_SPc
- serine endopeptidase
- peptidase
- Trypsin-like peptidase domain
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
role in cell
- accumulation in
- cell death
- generation in
- damage in
- damage
- vacuolation in
- condensation
- antibody-dependent cell-mediated cytotoxicity
- swelling in
- condensation in
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- lysosome
- granules