Tmem123 Gene Summary [Mouse]
Predicted to be located in external side of plasma membrane. Predicted to be active in cytoplasmic vesicle. Orthologous to human TMEM123 (transmembrane protein 123). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Tmem123 |
| Official Name | transmembrane protein 123 [Source:MGI Symbol;Acc:MGI:1919179] |
| Ensembl ID | ENSMUSG00000050912 |
| Bio databases IDs | |
| Aliases | transmembrane protein 123 |
| Synonyms | 2310075C12Rik, KCT3, PORIMIN, PORMIN, RGD1305625, transmembrane protein 123 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Tmem123 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Multi-glycosylated core protein 24 (MGC-24), sialomucin
- YXX-Phi motif
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- breast cancer
- COVID-19
role in cell
- expression in
- cell death
- adherence
- permeability
- structural integrity
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- cell surface
- cellular membrane
- plasma membrane extracellular face
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Tmem123 gene, providing context for its role in the cell.
Cellular Component
Where in the cell the gene product is active
- membrane
- external side of plasma membrane
- cytoplasmic vesicle
Molecular Function
What the gene product does at the molecular level
- protein binding
- signaling receptor activity