Cdh9 Gene Summary [Mouse]
Enables cadherin binding activity involved in cell-cell adhesion and identical protein binding activity. Involved in synapse assembly and synaptic membrane adhesion. Located in axon and dendrite. Is active in glutamatergic synapse; hippocampal mossy fiber to CA3 synapse; and synaptic membrane. Is expressed in several structures, including limb; nervous system; sensory organ; and testis. Orthologous to human CDH9 (cadherin 9). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Cdh9 |
| Official Name | cadherin 9 [Source:MGI Symbol;Acc:MGI:107433] |
| Ensembl ID | ENSMUSG00000025370 |
| Bio databases IDs | |
| Aliases | cadherin 9 |
| Synonyms | cadherin 9, T1-cadherin |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Cdh9 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Cadherin, Y-type LIR-motif
- cell adhesion molecule binding
- Cadherin repeat-like domain
- cadherin binding
- identical protein binding
Pathways
Biological processes and signaling networks where the Cdh9 gene in mouse plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- glutaminergic synapse
- cellular membrane
- presynaptic membrane
- postsynaptic membrane
- synapse
- axons
- dendrites
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Cdh9 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- calcium-dependent cell-cell adhesion
- synapse assembly
- cell-cell junction assembly
- adherens junction organization
- multicellular organismal development
- cell morphogenesis
- cell-cell adhesion mediated by cadherin
- homophilic cell adhesion
- cell migration
Cellular Component
Where in the cell the gene product is active
- presynaptic membrane
- adherens junction
- postsynaptic membrane
- catenin complex
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- calcium ion binding
- cadherin binding
- beta-catenin binding