MT-RNR2 Gene Summary [Human]
Enables G protein-coupled receptor binding activity; protein self-association; and receptor antagonist activity. Involved in several processes, including leukocyte chemotaxis; negative regulation of cell death; and negative regulation of neuroinflammatory response. Located in several cellular components, including mitochondrion; perinuclear region of cytoplasm; and sperm midpiece. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Mitochondrial Ribosomal RNA |
| Official Symbol | MT-RNR2 |
| Official Name | mitochondrially encoded 16S rRNA [Source:HGNC Symbol;Acc:HGNC:7471] |
| Ensembl ID | ENSG00000210082 |
| Bio databases IDs | |
| Aliases | mitochondrially encoded 16S rRNA, humanin, formyl-humanin |
| Synonyms | 16S, 16S ribosomal RNA, ENSMUSG00000064339, l-rRNA, mt-Rnr2-201, RNR2 |
| Species | Human, Homo sapiens |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human MT-RNR2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- structural constituent of ribosome
Pathways
Biological processes and signaling networks where the MT-RNR2 gene in human plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- myelodysplastic syndrome
- neoplastic cell transformation
- Huntington disease
- diabetic nephropathy
- mitochondrial disorder
- pigmented villonodular synovitis
role in cell
- apoptosis
- translation in
- expression in
- transcription in
- destruction
- binding in
- tumorigenicity
- consumption in
- destruction in
- action potential in
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- ribosome