PANDAR Gene Summary [Human]
This gene produces a non-coding RNA that is thought to regulate the response to DNA damage. This gene is induced by tumor protein p53 and interacts with and modulates the activity of a transcription factor that induce pro-apoptotic genes. Deregulation of this gene is associated with cancer progression. [provided by RefSeq, Dec 2017]
Details
| Type | Long Non-Coding RNA |
| Official Symbol | PANDAR |
| Official Name | promoter of CDKN1A antisense DNA damage activated RNA [Source:HGNC Symbol;Acc:HGNC:44048] |
| Ensembl ID | ENSG00000281450 |
| Bio databases IDs | |
| Aliases | promoter of CDKN1A antisense DNA damage activated RNA, p21 associated ncRNA DNA damage activated |
| Synonyms | p21-associated ncRNA DNA damage activated, PANDA, PANDA antisense, promoter of CDKN1A antisense DNA damage activated RNA |
| Species | Human, Homo sapiens |
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- neoplasia
- non-small cell lung cancer
- non-small cell lung carcinoma
- breast cancer
- organismal death
- cholangiocarcinoma
- cholangiocarcinoma cancer
regulated by
- TP53
- doxorubicin
- curcumin
role in cell
- expression in
- proliferation
- apoptosis
- migration
- binding in
- invasion by
- senescence
- G1/S phase transition
- sensitization
- epithelial-mesenchymal transition in
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Unknown