ST7L Gene Summary [Human]

This gene was identified by its similarity to the ST7 tumor suppressor gene found in the chromosome 7q31 region. This gene is clustered in a tail-to-tail manner with the WNT2B gene in a chromosomal region known to be deleted and rearranged in a variety of cancers. Several transcript variants encoding many different isoforms have been described, but some have not been fully characterized. [provided by RefSeq, Feb 2011]

Details

Type
Nonsense Mediated Decay
Official Symbol
ST7L
Official Name
suppression of tumorigenicity 7 like [Source:HGNC Symbol;Acc:HGNC:18441]
Ensembl ID
ENSG00000007341
Bio databases IDs NCBI: 54879 Ensembl: ENSG00000007341
Aliases suppression of tumorigenicity 7 like
Synonyms FAM4B, ST7R, STLR, suppression of tumorigenicity 7-like, suppression of tumourigenicity 7-like
Species
Human, Homo sapiens
OrthologiesMouseRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human ST7L often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Suppression of tumorigenicity 7
  • tetratricopeptide repeat
  • ST7 protein

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • cancer
  • open-angle glaucoma
  • pancreatic carcinoma
  • cervical cancer
  • pancreatic epithelial cancer
  • chondrosarcoma
role in cell
  • growth

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Unknown

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human ST7L gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • negative regulation of cell growth

Cellular Component

Where in the cell the gene product is active
  • membrane

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.