SLC39A9 Gene Summary [Human]
Predicted to enable metal ion transmembrane transporter activity. Predicted to be involved in transmembrane transport and zinc ion transport. Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Processed Transcript |
| Official Symbol | SLC39A9 |
| Official Name | solute carrier family 39 member 9 [Source:HGNC Symbol;Acc:HGNC:20182] |
| Ensembl ID | ENSG00000029364 |
| Bio databases IDs | |
| Aliases | solute carrier family 39 member 9 |
| Synonyms | 2010002A02Rik, 2610511I23Rik, 4833420E20RIK, solute carrier family 39 member 9, solute carrier family 39, member 9, solute carrier family 39 (zinc transporter), member 9, ZIP-9 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human SLC39A9 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- G-protein coupled receptor
- ZIP Zinc transporter
- protein binding
- zinc ion transporter
- cation efflux permease
- androgen binding
- transporter
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- neoplasia
- breast cancer
- metastasis
- organismal death
- bladder cancer
- prostate cancer
regulated by
- keratinocytes
- mir-96
- mir-183
- mir-182
- N,N,N',N'-tetrakis(2-pyridyl-methyl)ethylenediamine
role in cell
- apoptosis
- binding
- phosphorylation in
- expression in
- binding in
- production in
- cell death
- activation in
- migration
- invasion by
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- perinuclear region
- Nucleus
- Plasma Membrane
- Mitochondria
- trans Golgi network
- mitochondrial membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human SLC39A9 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- G-protein coupled receptor signaling pathway
- tight junction assembly
- cellular zinc ion homeostasis
- regulation of cellular response to testosterone stimulus
- zinc ion transmembrane transport
Cellular Component
Where in the cell the gene product is active
- nucleus
- trans-Golgi network
- mitochondrial membrane
- perinuclear region of cytoplasm
- mitochondrion
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- G-protein coupled receptor activity
- protein binding
- zinc ion transmembrane transporter activity
- androgen binding
- zinc efflux transmembrane transporter activity