ANKRD46 Gene Summary [Human]

This gene encodes a protein containing multiple ankyrin repeats. Ankyrin domains function in protein-protein interactions in a variety of cellular processes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2012]

Details

Type
Protein Coding
Official Symbol
ANKRD46
Official Name
ankyrin repeat domain 46 [Source:HGNC Symbol;Acc:HGNC:27229]
Ensembl ID
ENSG00000186106
Bio databases IDs NCBI: 157567 Ensembl: ENSG00000186106
Aliases ankyrin repeat domain 46
Synonyms 1110054N06RIK, ANK-S, ankyrin repeat domain 46, GENX-115279, RGD1309382
Species
Human, Homo sapiens
OrthologiesMouseRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human ANKRD46 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • transcription regulator
  • Ankyrin repeats (many copies)
  • Ankyrin repeats (3 copies)
  • protein binding
  • Ankyrin repeat
  • ankyrin repeats

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • non-insulin-dependent diabetes mellitus
  • systemic sclerosis
  • lung cancer
  • mild cognitive impairment
regulated by

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human ANKRD46 gene, providing context for its role in the cell.

Cellular Component

Where in the cell the gene product is active
  • membrane

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.