SFXN5 Gene Summary [Human]

Predicted to enable citrate transmembrane transporter activity. Predicted to be involved in citrate transport and mitochondrial transmembrane transport. Located in mitochondrion. [provided by Alliance of Genome Resources, Apr 2022]

Details

Type
Processed Transcript
Official Symbol
SFXN5
Official Name
sideroflexin 5 [Source:HGNC Symbol;Acc:HGNC:16073]
Ensembl ID
ENSG00000144040
Bio databases IDs NCBI: 94097 Ensembl: ENSG00000144040
Aliases sideroflexin 5
Synonyms BBG-TCC, C230001H08Rik, sideroflexin 5, SLC56A5, SLC64A5
Species
Human, Homo sapiens
OrthologiesMouseRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human SFXN5 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Sideroflexins
  • protein binding
  • transporter
  • citrate transporter

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • schizophrenia
regulated by
regulates
  • citric acid

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • Mitochondria
  • mitochondrial membrane
  • mitochondrial inner membrane

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human SFXN5 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • ion transmembrane transport
  • citrate transport
  • amino acid transport

Cellular Component

Where in the cell the gene product is active
  • mitochondrion
  • mitochondrial inner membrane

Molecular Function

What the gene product does at the molecular level
  • citrate transmembrane transporter activity
  • protein binding
  • ion transmembrane transporter activity

Gene-Specific Assays for Results You Can Trust

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