MCUR1 Gene Summary [Human]
Involved in calcium import into the mitochondrion and positive regulation of mitochondrial calcium ion concentration. Is integral component of mitochondrial inner membrane. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | MCUR1 |
| Official Name | mitochondrial calcium uniporter regulator 1 [Source:HGNC Symbol;Acc:HGNC:21097] |
| Ensembl ID | ENSG00000050393 |
| Bio databases IDs | |
| Aliases | mitochondrial calcium uniporter regulator 1 |
| Synonyms | 6230416A05Rik, AW554392, C6orf79, CCDC90A, FMP32, LOC100506556, mitochondrial calcium uniporter regulator 1, RGD1307673 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human MCUR1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- binding protein
- protein binding activity, bridging
- protein binding
- Coiled-coil domain-containing protein 90-like
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Mitochondria
- mitochondrial inner membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human MCUR1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- calcium ion import
- elevation of mitochondrial calcium ion concentration
- mitochondrial calcium ion transport
Cellular Component
Where in the cell the gene product is active
- mitochondrion
- mitochondrial inner membrane
Molecular Function
What the gene product does at the molecular level
- protein binding