FAM50A Gene Summary [Human]
This gene belongs to the FAM50 family. The encoded protein is highly conserved in length and sequence across different species. It is a basic protein containing a nuclear localization signal, and may function as a DNA-binding protein or a transcriptional factor. [provided by RefSeq, Sep 2009]
Details
| Type | Protein Coding |
| Official Symbol | FAM50A |
| Official Name | family with sequence similarity 50 member A [Source:HGNC Symbol;Acc:HGNC:18786] |
| Ensembl ID | ENSG00000071859 |
| Bio databases IDs | |
| Aliases | family with sequence similarity 50 member A, DNA segment on chromosome X (unique) 9928 expressed sequence |
| Synonyms | 9F, D0HXS9928E, DXS9928E, family with sequence similarity 50 member A, family with sequence similarity 50, member A, HXC-26, MRXSA, RGD1560964, XAP-5 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human FAM50A often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- neoplasia
- schizophrenia
- Armfield type X-linked mental retardation syndrome
- Turner syndrome
- mental retardation
- hereditary disorder
role in cell
- formation
- formation in
- fitness
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human FAM50A gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- RNA splicing
- regulation of RNA splicing
- spermatogenesis
- mRNA processing
- chromatin organization
Cellular Component
Where in the cell the gene product is active
- nucleus
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- protein binding
- RNA binding