Fam50a Gene Summary [Mouse]
Predicted to be involved in chromatin organization and regulation of RNA splicing. Predicted to be located in nucleoplasm. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in Armfield syndrome. Orthologous to human FAM50A (family with sequence similarity 50 member A). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Fam50a |
| Official Name | family with sequence similarity 50, member A [Source:MGI Symbol;Acc:MGI:1351626] |
| Ensembl ID | ENSMUSG00000001962 |
| Bio databases IDs | |
| Aliases | family with sequence similarity 50, member A |
| Synonyms | 9F, D0HXS9928E, DXS9928E, family with sequence similarity 50 member A, family with sequence similarity 50, member A, HXC-26, MRXSA, RGD1560964, XAP-5 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Fam50a often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- neoplasia
- schizophrenia
- Armfield type X-linked mental retardation syndrome
- Turner syndrome
- mental retardation
- hereditary disorder
role in cell
- formation
- formation in
- fitness
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Fam50a gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- RNA splicing
- regulation of RNA splicing
- spermatogenesis
- mRNA processing
- chromatin organization
Cellular Component
Where in the cell the gene product is active
- nucleus
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- protein binding
- RNA binding